Okay, this is a bad idea if your files are prefixed with ~
.
(add-hook 'ido-setup-hook (lambda () ;; Go straight home (define-key ido-file-completion-map (kbd "~") (lambda () (interactive) (if (looking-back "/") (insert "~/") (call-interactively 'self-insert-command))))))
But if they're not, this keybinding lets you even more quickly reach your home folder when in ido-find-file.
It doesn't matter if you're a million directories in, just press ~ to go home.