Like rename yesterday, I think delete deserves a designated keybinding.

(defun delete-current-buffer-file ()
  "Removes file connected to current buffer and kills buffer."
  (interactive)
  (let ((filename (buffer-file-name))
        (buffer (current-buffer))
        (name (buffer-name)))
    (if (not (and filename (file-exists-p filename)))
        (ido-kill-buffer)
      (when (yes-or-no-p "Are you sure you want to remove this file? ")
        (delete-file filename)
        (kill-buffer buffer)
        (message "File '%s' successfully removed" filename)))))

(global-set-key (kbd "C-x C-k") 'delete-current-buffer-file)

This is it. C-x C-k: file begone!

I like the feel between C-x k to kill the buffer and C-x C-k to kill the file. Release ctrl to kill it a little, hold to kill it a lot.